Table 3.
Swimming (min) | CPSM (mg kg−1) | vWF | VCAM-1 | ICAM-1 | |||
---|---|---|---|---|---|---|---|
Sham-operated | 0.11 ± 0.03 | 0.21 ± 0.04 | 0.15 ± 0.05 | ||||
0 | 0 | 0.43 ± 0.08 | 0.83 ± 0.26 | 0.67 ± 0.22 | |||
0 | 237 | 0.42 ± 0.13 | 0.64 ± 0.17 | 0.40 ± 0.12 | |||
0 | 474 | 0.53 ± 0.14 | 0.72 ± 0.22 | 0.38 ± 0.13 | |||
20 | 0 | 0.29 ± 0.05 | 0.45 ± 0.15 | 0.38 ± 0.12 | |||
20 | 237 | 0.34 ± 0.09 | 0.78 ± 0.23 | 0.63 ± 0.20 | |||
20 | 474 | 0.60 ± 0.17 | 0.63 ± 0.21 | 0.69 ± 0.19 | |||
40 | 0 | 0.34 ± 0.09 | 0.26 ± 0.08 | 0.14 ± 0.04 | |||
40 | 237 | 0.16 ± 0.03 | 0.519 ± 0.16 | 0.22 ± 0.07 | |||
40 | 474 | 0.15 ± 0.02 | 0.37 ± 0.10 | 0.35 ± 0.04 | |||
Two-way ANOVA | F | p | F | p | F | p | |
Swimming | 24.25 | <0.001 | 7.87 | <0.001 | 17.08 | <0.001 | |
CPSM | 5.82 | 0.01 | 6.70 | <0.001 | 2.39 | 0.10 | |
CPSM × swimming | 9.29 | <0.001 | 8.59 | <0.001 | 3.62 | 0.01 |
Expression of vWF, VCAM-1, and ICAM-1were normalized with respect to β-actin.
All data are expressed as the mean ± SD. The GLM procedure was applied for a two-way ANOVA to test for synergy. Comparisons between each pair of factor levels were analyzed using a Bonferroni post hoc test. A value of p < 0.05 was considered statistically significant.