Table 1.
Characteristics of 30 patients with acute respiratory distress syndrome induced or not by coronavirus disease-19
| C-ARDS (n = 17) | NC-ARDS (n = 13) | p value | |
|---|---|---|---|
| Patients' characteristics | |||
| Age (years) | 54 [50, 67] | 69 [53, 71] | 0.15 |
| Male, n (%) | 16/17 (94%) | 11/13 (85%) | 0.56 |
| Weight (kg) | 90 [80, 106] | 80 [66, 90] | 0.07 |
| Body mass index, kg/m2 | 30.2 [27.8, 33.2] | 28.7 [24.8, 31.1] | 0.16 |
| History of COPD, n (%) | 1/17 (6%) | 1/13 (8%) | > 0.99 |
| History of chronic heart failure, n (%) | 3/17 (18%) | 4/13 (31%) | 0.67 |
| History of chronic kidney failure, n (%) | 3/17 (18%) | 3/13 (23%) | > 0.99 |
| Immunosuppression, n (%) | 1/17 (6%) | 2/13 (15%) | 0.56 |
| Time from first symptoms to intubation (days) | 9 [6.5, 10] | NA | |
| SAPS 2 | 34 [27, 38] | 62 [42, 83] | 0.01 |
| PaO2/FiO2 at intubation (mmHg) | 98 [90, 144] | 135 [80, 182] | 0.64 |
| CT scan and echocardiography | |||
| Presence of lung consolidation on CT scan, n (%) | 2/11 (18%) | 4/5 (80%) | 0.04 |
| Pulmonary embolism on CT angiography, n (%) | 3/8 (38%) | 1/5 (20%) | > 0.99 |
| Acute cor pulmonale on echocardiography, n (%) | 8/17 (47%) | 1/13 (8%) | 0.04 |
| Patent foramen ovale, n (%) | 1/17 (6%) | 0 | > 0.99 |
| Outcomes | |||
| Need for vasopressor, n (%) | 11/17 (65%) | 11/13 (85%) | 0.41 |
| ECMO upon ICU stay, n (%) | 2/17 (12%) | 1/13 (8%) | > 0.99 |
| Tracheotomy during ICU stay, n (%) | 3/17 (18%) | 0 | 0.24 |
| Duration of mechanical ventilation (days) | 13 [9, 29] | 13 [8, 22] | 0.53 |
| Duration of ICU stay (days) | 18 [12, 30] | 17 [11, 22] | 0.75 |
| Death in ICU, n (%) | 4/17 (24%) | 6 /13 (46%) | 0.26 |
Continuous variables are expressed as median [interquartile range]
C-ARDS coronavirus disease-19-related acute respiratory distress syndrome, NC-ARDS noncoronavirus disease-19-related acute respiratory distress syndrome, BMI body mass index, COPD chronic obstructive pulmonary disease, SAPS simplified acute physiology score, CT computed tomography, ECMO extracorporeal membrane oxygenation, ICU intensive care unit, NA not available