Table 4.
Comparison of PEEP titration in supine versus prone position, for patients with coronavirus disease-19-related acute respiratory distress syndrome
| C-ARDS in supine position (n = 14) | C-ARDS in prone position (n = 14) | p value | |
|---|---|---|---|
| PaO2/FiO2 (mmHg) | 107 [93, 136] | 179 [127, 190] | < 0.01 |
| EIT-PEEP titration | |||
| Best PEEPa (cmH2O) | 12 [9, 12] | 12 [10, 15] | 0.59 |
| AUC for compliance | 344 [316, 439] | 455 [332, 494] | 0.04 |
| Hyperdistension at PEEP 18 cm H2O (%) | 24 [17, 30] | 17 [15, 41] | 0.63 |
| AUC for hyperdistension | 113 [68, 134] | 80 [40, 194] | 0.82 |
| Collapse at PEEP 6 cm H2O (%) | 23 [19, 37] | 35 [23, 42] | 0.07 |
| AUC for collapse | 86 [58, 139] | 173 [135, 261] | < 0.01 |
aDefined using EIT as the smallest sum of hyperdistension and collapse. Continuous variables are expressed as median [interquartile range]
PEEP positive end-expiratory pressure, EIT electrical impedance tomography, AUC area under the curve in supine and prone position (see Fig. 4)