Table 3.
Clinical and laboratory characteristics of suspected COVID-19
| Clinical characteristics | Patient 1 | Patient 2 | Patient 3 | Patient 4 |
|---|---|---|---|---|
| Residence | Hangzhou | Hangzhou | Lishui | Shaoxing |
| Date of admission | 1-Feb 2020 | 27-Feb 2020 | 9-Mar 2020 | 17-Mar 2020 |
| Age (years) | 78 | 56 | 42 | 43 |
| Gender | Male | Male | Female | Female |
| Cancer type | Esophageal cancer | Hypopharyngeal cancer | Lung cancer | Breast cancer |
| Smoking status | Yes | Yes | No | No |
| Epidemiological history | Yes (Exposure to relevant environment) | No | No | No |
| Other diseases | No | No | Yes (Ovarian cancer and liver cancer) | No |
| Treatment history | Chemoradiotherapy 2 months ago | Chemoradiotherapy 2 months ago | Chemotherapy 1 month ago | Chemotherapy 3 weeks ago |
| Symptoms | ||||
| Fever | Yes(37.3 °C) | Yes(38.3 °C) | Yes(37.7 °C) | Yes(38.2 °C) |
| Cough | Yes | Yes | Yes | No |
| Fatigue or myalgia | No | Yes | Yes | No |
| Expectoration | Yes | Yes | Yes | No |
| Dyspnea | No | No | No | No |
| Headache | No | Yes | No | No |
| Diarrhea | No | No | No | No |
| Laboratory characteristics | ||||
| White blood cell count (× 109 cells per L) | 5 | 7.6 | 12.8 | 5.7 |
| Low leukocyte count (< 9·5 × 109 cells per L) | No | No | No | No |
| Lymphocyte count (× 109 cells per L) | 0.8 | 0.4 | 1.2 | 0.7 |
| Lymphopenia (< 109 cells per L) | Yes | Yes | No | Yes |
| CRP (mg/L) | 11.12 | 31.04 | 12.25 | 9.21 |
| Elevated CRP (> 10 mg/L) | Yes | Yes | Yes | No |
| LDH (U/L) | 141 | 337 | 199 | 296 |
| Elevated LDH (> 240 U/L) | No | Yes | No | Yes |
| ALT (U/L) | 23 | 17 | 10 | 51 |
| Elevated ALT (> 50 U/L) | No | No | No | Yes |
| AST (U/L) | 26 | 30 | 25 | 48 |
| Elevated AST (> 40 U/L) | No | No | No | Yes |
| CT evidence of pneumonia | ||||
| Typical signs of viral infection | Positive | Positive | Positive | Positive |
| 1st round of PCR | ||||
| RNA-dependent RNA polymerase (RdRp) | Negative | Negative | Negative | Negative |
| Nucleocapsid (N) gene | Positive | Negative | Negative | Negative |
| 2nd round of PCR after 24 h | ||||
| RNA-dependent RNA polymerase (RdRp) | Negative | Negative | Negative | Negative |
| Nucleocapsid (N) gene | Negative | Negative | Negative | Negative |
| Follow-up Treatment | ||||
| Anti-infection therapy | Hormone therapy | Anti-infection therapy and Chemotherapy | Transfer to local hospital | |
CRP C-reactive protein. LDH Lactate dehydrogenase. ALT Alanine transaminase. AST Aspartate transaminase