Table 1.
Patient characteristics of total cohort and subcohorts with and without thromboembolic events
| Cohort (n = 40) | Thromboembolic events (N = 23) | No thromboembolic events (N = 17) | p value | ||||
|---|---|---|---|---|---|---|---|
| Age (years, (median, [IQR])) | 67 | [57.3–76.6] | 66 | [56–76] | 68 | [62–77.5] | ns |
| Gender, male (n, %) | 35 | 87.5% | 20 | 87% | 15 | 88% | ns |
| BMI, kg/m2 (median, [IQR]) | 28.1 | [24.8–32.8] | 27.8 | [24.2–33] | 28.7 | [25.7–32.3] | ns |
| Duration of ICU stay, days (median, [IQR]) | 39.5 | [24–54.25] | 42 | [28–58] | 25 | [8.5–47.5] | 0.05 |
| Death during ICU stay (n, %) | 11 | 27.5% | 9 | 39.1% | 2 | 11.8% | 0.58 |
| Intubation (n, %) | 31 | 77.5% | 20 | 87% | 11 | 65% | ns |
| ECMO (n, %) | 10 | 25% | 9 | 39.1% | 1 | 6% | ns |
| CRRT (n, %) | 21 | 52.5% | 16 | 69.6% | 5 | 29.4% | 0.013 |
| SOFA score (median, [IQR]) | 9 | [6.3–11.8] | 10 | [6–11] | 8 | [4.5–11] | ns |
| SIC score (median, [IQR]) | 3 | [2–4] | 3 | [2–4] | 3 | [2–4] | ns |
| APACHE score (median, [IQR]) | 28 | [22–33] | 29 | [23–34] | 26 | [19–31.8] | ns |
| Preexisting conditions | |||||||
| Coronary artery disease (n, %) | 9 | 22.5% | 6 | 26% | 3 | 18% | ns |
| Hypertension (n, %) | 25 | 62.5% | 14 | 61% | 11 | 65% | ns |
| Diabetes mellitus/insulin resistance (n, %) | 13 | 32.5% | 10 | 43% | 3 | 18% | ns |
| Chronic kidney disease (n, %) | 7 | 17.5% | 6 | 26% | 1 | 6% | ns |
| Chronic dialysis (n, %) | 1 | 2.5% | 1 | 4% | 0 | 0% | ns |
| Lung disease (n, %) | 7 | 17.5% | 6 | 26% | 1 | 6% | ns |
ECMO Extracorporeal membrane oxygenation, SOFA sequential organ failure assessment, CRRT continuous renal replacement therapy, SIC sepsis-induced coagulopathy, APACHE acute physiology and chronic health evaluation