Table 4.

Histological ultrastructural features in our cohort of patients, where available.

Pts	Thinning	Thickening	Lamellation	Basket weave lesions
GROUP 1—patients with Mild mutations
1	+	+	+	–
2	+	+	+	+
3
4
5
6	++	–	+	–
7
8	++	–	+	–
9	+	–	+	–
10	+	+	+	+
GROUP 2—patients with Severe mutations
1	+	–	+	–
2	+	+	+	–
3
4	+	+	+	–
5
6	+	+	++	++
7	+	–	+	+
8	++	+	+	+
9	++	+	+	+
10	++	–	+	++
11	+	+	+	+
12
13
14	+	+	+	–

+focal distribution of the feature.

++a diffuse distribution of the feature.