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. 2020 Nov 23;10:578809. doi: 10.3389/fonc.2020.578809

Figure 2.

Figure 2

Establishment and verification of LGG grouping. (A) The heatmap showed the unsupervised clustering of 29 immune-associated gene sets in the high immune group (Immunity_H) and the low immune group (Immunity_L). Parameters including tumor purity, ESTIMATE scores, immune scores, and stromal scores. (B) The histogram showed the differences in expression levels of HLA and family gene between the high and low immunity groups. (C) The violin diagram showed the difference in tumor purity, ESTIMATE scores, immune scores and stromal scores. (D) The CIBERSORT algorithm obtained that the infiltration level of most immune-related cells in the high immune group is lower than that in the low immune group, such as Dendritic cells resting, Macrophages M1, Macrophages M2, Mast cells resting, NK cells resting, T cells CD4 memory activated, T cells CD8, and T cells gamma delta. *p < 0.05; **p < 0.01; ***p < 0.001.