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. 2020 Nov 23;11:597741. doi: 10.3389/fimmu.2020.597741

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Copyright © 2020 Wu, Del Duca, Espino, Gontzes, Cueto, Zhang, Estrada, Pavel, Krueger and Guttman-Yassky

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative immunohistochemistry images and corresponding cell count quantification of IL-4Rα⁺ cells (A–D), tryptase⁺ mast cells (E–H), CCR9⁺ cells (I–L) and periostin⁺ cells (M–P) in normal skin from controls, and lesional and non-lesional skin of keloid patients, viewed at 10x magnification. Red bar represents mean. Black symbols: significance of comparison to normal; red symbols: significance of comparison between lesional and non-lesional skin. **P < 0.01, *P < 0.05, ⁺ P < 0.1. LS, lesional; NL, non-lesional; N, normal.