Table 2.

Examples of genomic alterations associated with survival outcome in a single sex or in both sexes with opposite effect.

Gene	Type of alteration	Prognostic value	Cancer	Reference
RPL37A	expression	only in females	colon	Li et al. (70)
SRGAP1	expression	only in males	colon	Li et al. (70)
ACTL7B	expression	both sexes, but in opposite directions	colon	Li et al. (70)
TRRAP	expression	both sexes, but in opposite directions	colon	Li et al. (70)
LATS1	CNA and expression	only in females	kidney clear cell	Li et al. (70)
UBAC1	CNA and expression	only in females	kidney clear cell	Li et al. (70)
C16orf45	CNA and expression	only in females	kidney papillary cell	Li et al. (70)
LCMT1	CNA and expression	only in females	kidney papillary cell	Li et al. (70)
BRAF	mutation	only in males	colorectal	Wangefjord et al. (71)
BAP1	mutation	only in females	kidney clear cell	Ricketts and Linehan (72)
TP53	mutation	only in females	colon	Warren et al. (73)
miR-192, miR-206, miR-194, and miR-219	expression	only in females	colorectal	Garufi et al. (74)

CNA, copy number alteration.