Table 2. Comparison of electroretinography a and b wave amplitudes among eight experimental groups.
Experimental groups | Pre | Post-8 wks | Preservation | Pre | Post-8 wks | Preservation |
---|---|---|---|---|---|---|
a wave (μV) | a wave (μV) | a wave (%) | b wave (μV) | b wave (μV) | b wave (%) | |
Normal control (n=6) | 183.2 ± 40.24 a) | 210.3 ± 24.48 a) | 114.79 ± 10.18 a) | 365.2 ± 68.56 a) | 346.5 ± 53.48 a) | 94.88 ± 3.95 a) |
Untreated IR injury (n=6) | 209.1 ± 10.74 a) | 73.4 ± 11.62 b) | 35.10 ± 7.53 b) | 384.7 ± 61.99 a) | 103.5 ± 11.37 b) | 26.90 ± 4.42 b) |
Blended (500 mg/kg) (n=6) | 183.2 ± 45.61 a) | 122.1 ± 18.62 c) | 66.65 ± 6.75 cd) | 365.2 ± 64.50 a) | 212.6 ± 46.64 c) | 58.21 ± 7.26 c) |
Blended (250 mg/kg) (n=6) | 173.8 ± 22.63 a) | 105.8 ± 4.57 c) | 60.87 ± 6.17 cd) | 374.5 ± 54.65 a) | 163.2 ± 35.78 d) | 43.58 ± 6.71 d) |
Blended (100 mg/kg) (n=6) | 157.5 ± 32.72 a) | 93.3 ± 12.59 c) | 59.24 ± 9.06 c) | 348.4 ± 63.92 a) | 198.4 ± 35.22 cd) | 56.95 ± 5.18 cd) |
Milled (500 mg/kg) (n=6) | 186.5 ± 32.34 a) | 103.5 ± 20.32 c) | 55.5 ± 7.09 c) | 386.7 ± 44.88 a) | 193.6 ± 19.47 cd) | 50.06 ± 5.68 d) |
Milled (250 mg/kg) (n=6) | 194.6 ± 25.43 a) | 132.7 ± 15.04 c) | 68.19 ± 5.11 cd) | 405.6 ± 37.30 a) | 253.8 ± 27.92 e) | 62.57 ± 4.80 e) |
Milled (100 mg/kg) (n=6) | 202.4 ± 29.65 a) | 137.3 ± 22.81 c) | 67.84 ± 3.08 cd) | 397.4 ± 55.81 a) | 217.5 ± 14.18 cd) | 54.73 ± 4.14 d) |
Eight experimental groups include normal control group, untreated IR injury group, blended groups: 500 mg/kg, 250 mg/kg, 100 mg/kg; and milled (submicron) groups: 500 mg/kg, 250 mg/kg, 100 mg/kg. pre, before IR injury; post-8 wks, 8 weeks after IR injury; preservation, the preservation ratio of a or b wave amplitudes in LB treatment groups, untreated IR injury group and normal control group in 8 weeks after IR injury (The preservation ratio=a or b wave amplitude of post-8 wks/ a or b wave amplitude before IR injury). Data are shown as Mean ± SD and evaluation by one-way ANOVA followed by Scheffe’s multiple comparison test. n=6 in each group. The data with different superscript alphabetical letters indicate significantly statistical difference (P<0.05) between groups. The data with the same superscript letters indicate no significant difference (P>0.05) between groups.