Table 2. Means and standard deviations of the semi-quantitative parameters of glioma volume of interest (VOI) delineation based on static O-(2-[18F]fluoroethyl)-l-tyrosine positron emission tomography imaging in different tumor grades and isocitrate dehydrogenase gene 1 (IDH1) status.
| Parameters | Grades II and III | Grade IV | IDH wild type | IDH mutation |
|---|---|---|---|---|
| TBRmax | 2.82±1.04 | 4.63±1.92 | 3.49±1.63 | 2.68±0.91 |
| TBRpeak | 2.44±0.88 | 4.01±1.53 | 3.00±1.35 | 2.36±0.79 |
| TBRmean | 1.92±0.28 | 2.32±0.45 | 2.06±0.39 | 1.91±0.26 |
| COV*100 | 12.72±9.15 | 26.05±12.7 | 17.72±12.15 | 11.53±8.43 |
| HI | 1.43±0.31 | 1.94±0.54 | 1.62±0.46 | 1.37±0.28 |
| MTV | 20.96±37.63 | 50.88±44.89 | 30.12±35.10 | 21.93±49.57 |
| TLU | 39.81±67.68 | 108.84±88.51 | 63.29±71.86 | 37.88±84.59 |
| SUVsd | 0.258±0.230 | 0.618±0.385 | 0.407±0.336 | 0.200±0.173 |
COV, coefficient of variation; HI, heterogeneity index; MTV, metabolic tumor volume; SUVsd, standard deviation of lesion standardized uptake value; TBRmax, maximal tumor-to-background ratio; TBRmean, mean tumor-to-background ratio; TBRpeak, peak tumor-to-background ratio; TLU, total lesion tracer standardized uptake.