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. 2021 Jan;11(1):43–56. doi: 10.21037/qims-19-954

Figure 5.

Figure 5

Serial progression and perfusion features of H3 K27M-mutant diffuse midline glioma. Case 7: T2w (A), FLAIR (B), ADC map (C) and post gadolinium T1w images (D) performed on admission showing a non-gadolinium enhancing tumour with ADC signal approximately isointense to surrounding brain. The same patient after 7 months: T2w (E, featuring volumetric segmentation example), FLAIR (F), post gadolinium T1w (G) and DSC perfusion-derived rCBV map (H) revealing interval progression with development of contrast enhancement and pathologically raised blood volume (arrow). ADC, apparent diffusion coefficient; DSC, dynamic susceptibility contrast enhanced perfusion MRI; rCBV, relative cerebral blood volume.