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. 2020 Dec 6;14(1):100981. doi: 10.1016/j.tranon.2020.100981

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© 2020 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 3 — Subpopulations of cancer-distinct fibroblasts. (a) UMAP plot showing the expression of fibroblast cell marker, ACTA2, across all the cell lineages. (b) Volcano plot of differential expressed genes between the two clusters of cancer-distinct fibroblasts (Cluster 15 and Cluster 19). (c) Violin plots of the top-ranking differential expressed genes between the two clusters of cancer-distinct fibroblasts (Cluster 15 and Cluster 19). (d) Gene ontology analysis of genes highly expressed in Cluster 19. (e) Violin plots showing the expression of marker genes across the fibroblast cell clusters (C15, C19) and endothelial cell clusters (C8, C11, C18).