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. Author manuscript; available in PMC: 2020 Dec 7.
Published in final edited form as: Eur J Immunol. 2014 Nov;44(11):3330–3341. doi: 10.1002/eji.201444675

Figure 4.

Figure 4.

Secretion of IL-17 with different treatments. On day 19 after EAE induction splenocytes from EAE mouse were stimulated with MOG peptide and IL-17 secretion was detected by ELISA. (A) TMβ-1 (TMb-1) or control rat IgG (Rat IgG) treated groups were examined. (B) IL-15−/− mice and wild type (WT) animals were examined. (C) IL-17 secretion by transfer of naïve CD8+CD122+ T cells (naïve CD8+CD122+) and nontransferred control group (Control) are shown. (D) IL-17 secretion by preactivated CD8+CD122+/CD8+CD122− T cells transferred groups (Activated CD8+CD122+/Activated CD8+CD122−) are shown. Nontransferred control group (Control) were provided as control. Data are shown as mean ± SD of three to five mice from a single experiment representative of three experiments performed. *p < 0.05 compared to control group (Student’s t-test).