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. 2020 Oct 12;10(4):164. doi: 10.3390/jpm10040164

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Selected examples of serum protein PD biomarkers showing difference between prednisone (Pred) and deflazacort (Dfz)-treated samples. FCN-1 has relatively higher mean RFU levels in Dfz-treated patients (p = 0.038 for mean levels; p = 0.03 for difference in trajectory slopes over time). TNFRSF21 has higher mean RFU levels in Pred- vs. Dfz-treated DMD patients (p = 0.005 mean levels; p = 0.934 for difference in trajectory slopes over time). The longitudinal trajectories of IGFBP-2 levels are different between the two drugs (p = 0.04). MMP-3 mean RFU level is elevated in DMD boys treated with Dfz, as compared to Pred (p = 0.008).