Table 1.

The statistical results of additive model logistic regression analysis in the discovery and replication sets. CHR, chromosome. SNP, single nucleotide polymorphism. BP, physical position. A1, minor allele. TEST, logistic regression test method for the genetic model. OR, odds ratio. STAT, Coefficient t-statistic. P, p-value.

Information					Discovery			Replication
CHR	SNP	BP	A1	TEST	OR	STAT	p	OR	STAT	p
1	rs3007782	4,472,736	T	ADD	4.287	5.488	4.06 × 10−8	1.061	0.1557	0.8763
1	rs74918369	61,457,396	C	ADD	8.071	6.242	4.31 × 10−10	2.133	1.283	0.1994
1	rs115143460	1.9 × 108	A	ADD	13.33	7.047	1.83 × 10−12	3.37 × 10−9	0.0009	0.9993
1	rs12026894	2.45 × 108	A	ADD	6.483	5.903	3.57 × 10−9	1.33	1.01	0.3125
2	rs12615054	22,223,766	G	ADD	7.526	6.069	1.29 × 10−9	0.9204	−0.2382	0.8117
2	rs141292341	37,310,903	T	ADD	10.14	6.5	8.05 × 10−11	1.38	0.4903	0.6239
2	rs145263938	87,842,313	T	ADD	5.618	5.956	2.58 × 10−9	0.5837	−1.115	0.2648
2	rs12692712	1.65 × 108	C	ADD	4.92	5.649	1.61 × 10−8	1.668	1.819	0.06891
2	rs79371157	2.28 × 108	T	ADD	9.601	6.56	5.38 × 10−11	0.812	−0.3447	0.7303
3	rs28630998	13,245,725	G	ADD	8.74	6.678	2.42 × 10−11	4.312	3.007	0.00264
3	rs2323277	74,110,248	A	ADD	11.5	6.684	2.33 × 10−11	1.209	0.4123	0.6801
4	rs141002338	24,750,774	C	ADD	10.45	6.536	6.32 × 10−11	0.5075	−1.032	0.3019
4	rs1510746	67,469,201	C	ADD	6.439	5.839	5.25 × 10−9	0.6251	−0.9697	0.3322
5	rs144522971	22,316,095	T	ADD	11.99	6.853	7.22 × 10−12	2.813	1.338	0.1811
5	rs296486	1.13 × 108	A	ADD	8.526	6.41	1.45 × 10−10	2.628	2.506	0.01222
6	rs117716146	16,032,432	T	ADD	11.65	6.789	1.13 × 10−11	0.8826	−0.1782	0.8585
6	rs111721931	1.1 × 108	G	ADD	13.21	7.047	1.83 × 10−12	1.26 × 10−9	−0.0019	0.9985
6	rs137945470	1.18 × 108	A	ADD	14.85	7.153	8.51 × 10−13	2.078	0.5152	0.6064
6	rs11759078	1.53 × 108	G	ADD	4.917	5.565	2.62 × 10−8	0.9774	−0.0669	0.9467
6	rs113416075	1.66 × 108	A	ADD	7.197	5.911	3.39 × 10−9	0.577	−1.466	0.1428
7	rs11761631	6,932,435	A	ADD	3.595	5.276	1.32 × 10−7	0.9426	−0.2598	0.795
7	rs3807170	37,898,032	T	ADD	6.065	5.735	9.76 × 10−9	0.721	−0.7404	0.4591
8	rs140245000	55,592,196	A	ADD	10.09	6.695	2.16 × 10−11	2.11	1.041	0.298
8	rs137854443	1.45 × 108	C	ADD	0.208	−5.769	7.99 × 10−9	NA	NA	NA
9	rs77096227	8,010,136	C	ADD	3.712	5.139	2.76 × 10−7	0.9232	−0.3035	0.7615
9	rs149748677	78,256,026	A	ADD	8.312	6.272	3.57 × 10−10	0.5173	−0.5861	0.5578
9	rs146186513	1.31 × 108	G	ADD	13.33	7.047	1.83 × 10−12	NA	NA	NA
9	rs77609276	1.38 × 108	T	ADD	8.534	6.201	5.60 × 10−10	0.7848	−0.4485	0.6538
10	rs78014704	1,842,302	T	ADD	9.568	6.59	4.39 × 10−11	0.5369	−1.34	0.1803
10	rs34498403	86,799,865	T	ADD	8.2	6.455	1.09 × 10−10	1.373	0.3439	0.7309
12	rs10877123	58,881,273	A	ADD	3.971	5.498	3.84 × 10−8	1.111	0.4515	0.6516
12	rs74650809	92,513,269	A	ADD	3.578	5.176	2.27 × 10−7	1.05	0.2121	0.8321
13	rs56238336	23,029,868	C	ADD	4.942	5.737	9.65 × 10−9	1.546	1.448	0.1476
13	rs146581261	1.11 × 108	A	ADD	14.3	6.992	2.71 × 10−12	1.682	0.9786	0.3278
14	rs1957293	92,708,417	A	ADD	4.209	5.448	5.10 × 10−8	1.068	0.2128	0.8315
15	rs78879506	37,133,840	A	ADD	10.6	6.534	6.39 × 10−11	1.125	0.3918	0.6952
15	rs57049930	93,855,283	T	ADD	5.072	5.615	1.97 × 10−8	0.9163	−0.2447	0.8067
16	rs77141302	54,570,512	C	ADD	4.301	5.826	5.68 × 10−9	1.138	0.4584	0.6466
16	rs149428	58,668,566	A	ADD	8.74	6.479	9.21 × 10−11	0.2768	−1.683	0.09247
17	rs146234219	9,038,490	T	ADD	13.33	7.047	1.83 × 10−12	3.36 × 10−9	0.0009	0.9993
17	rs17773918	11,399,739	G	ADD	8.535	6.425	1.32 × 10−10	3.569	1.718	0.08571
19	rs1715092	3,557,005	A	ADD	4.858	5.762	8.31 × 10−9	0.9295	−0.2799	0.7796
19	rs55941146	3,754,338	C	ADD	13.33	7.047	1.83 × 10−12	4.75	3.885	0.000102
19	rs918371	48,808,545	T	ADD	11.69	6.854	7.17 × 10−12	1.29 × 10−9	−0.0008	0.9993
21	rs16991683	35,800,134	A	ADD	4.26	5.47	4.49 × 10−8	0.7194	−1.104	0.2696