Table 4.

Association between microbiome variability and clinical outcome

	28-day all-cause mortality		Final hospital mortality
	Species	Genus	Species	Genus
Total (n = 60)
Bray–Curtis	0.15	0.63	0.45	0.24
Jaccard	0.33	0.57	0.48	0.22
Kulczynski	0.34	0.58	0.42	0.32
Gower	0.29	0.45	0.43	0.23
Pneumonia (n = 41)
Bray–Curtis	0.3	0.76	0.54	0.36
Jaccard	0.51	0.63	0.43	0.26
Kulczynski	0.5	0.69	0.28	0.3
Gower	0.29	0.63	0.38	0.44
Non-pneumonia (n = 19)
Bray–Curtis	0.65	0.14	0.65	0.14
Jaccard	0.66	0.5	0.66	0.5
Kulczynski	0.75	0.62	0.75	0.62
Gower	0.71	0.13	0.71	0.13

p values are from the MiRKAT. The quantitative and qualitative analyses (Bray–Curtis, Jaccard, Kulczynski and Gower analyses) were adjusted for sex, age, and APACHE II and CCI scores