Table 5.
GSTP1 wild type (n = 70) | GSTP1 mutant (n = 34) | |||
---|---|---|---|---|
Toxicities | G 1–2 | G 3–4 | G 1–2 | G 3–4 |
Hematological toxicity | ||||
Anemia | 31(29.8) | 14(13.5) | 15(14.4) | 5(4.8) |
Leucopenia | 35(33.7) | 7(6.7) | 13(12.5) | 3(2.9) |
Neutropenia | 30(28.8) | 13(12.5) | 9(8.7) | 3(2.9) |
Thrombocytopenia | 26(25.0) | 8(7.7) | 13(12.5) | 4(3.8) |
Gastrointestinal toxicity | ||||
Mucositis | 2(1.9) | 7(6.7) | 2(1.9) | 2(1.9) |
Vomiting | 22(21.2) | 12(11.5) | 5(4.8) | 11(10.6) |
Diarrhea | 8(7.7) | 7(6.7) | 4(3.8) | 2(1.9) |
Dermatology toxicity | ||||
Skin ulceration | 5(4.8) | 1(0.9) | 0(0) | 3(2.9) |
Hand-foot skin reaction | 8(7.7) | 2(1.9) | 3(2.9) | 3(2.9) |
Data are presented as n (%)