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. 2020 Dec 6;18:321. doi: 10.1186/s12957-020-02103-3

Table 5.

The frequency of all grade toxicities in patients with GSTP1 wild type and mutants

GSTP1 wild type (n = 70) GSTP1 mutant (n = 34)
Toxicities G 1–2 G 3–4 G 1–2 G 3–4
Hematological toxicity
 Anemia 31(29.8) 14(13.5) 15(14.4) 5(4.8)
 Leucopenia 35(33.7) 7(6.7) 13(12.5) 3(2.9)
 Neutropenia 30(28.8) 13(12.5) 9(8.7) 3(2.9)
 Thrombocytopenia 26(25.0) 8(7.7) 13(12.5) 4(3.8)
Gastrointestinal toxicity
 Mucositis 2(1.9) 7(6.7) 2(1.9) 2(1.9)
 Vomiting 22(21.2) 12(11.5) 5(4.8) 11(10.6)
 Diarrhea 8(7.7) 7(6.7) 4(3.8) 2(1.9)
Dermatology toxicity
 Skin ulceration 5(4.8) 1(0.9) 0(0) 3(2.9)
 Hand-foot skin reaction 8(7.7) 2(1.9) 3(2.9) 3(2.9)

Data are presented as n (%)