Table 6.

Events Leading to Discontinuation

Prior Treatment Status	Reason for Discontinuation of Ranibizumab	Reason for Study Discontinuation	Specification (Cause of Death or Adverse Event Specification)
TX-naïve	SAE	SAE	General deterioration
	SAE	death	Hypoglycemia
PRIOR-other	SAE	death	Metastatic oesophageal adenocarcinoma stage IV

Abbreviations: PRIOR-other, non-naïve eyes with other prior treatment(s); SAE, serious adverse event; TX-naïve, treatment-naïve eyes.