Skip to main content
. 2020 Dec 7;19:451. doi: 10.1186/s12936-020-03526-9

Table 5.

Presence of HRP2, pLDH-Pan, and pLDH-Pf antigen by type of result from RT-qPCR, cRDT and uRDT in 233 samples

HRP2 positive pLDH-Pan positive pLDH-Pf positive
N = 160/223 N = 114/223 N = 97/223
n (%) n (%) n (%)

RT-qPCR positive

N = 134/223

cRDT positive = TP N = 71 71 (100.0) 56 (78.9) 56 (78.9)
cRDT negative = FN N = 63 46 (73.0) 38 (60.3) 33 (52.4)
uRDT positive = TP N = 80 79 (98.8) 61 (76.3) 59 (73.8)
uRDT negative = FN N = 54 38 (70.4) 33 (61.1) 30 (55.6)

RT-qPCR negative

N = 89/223

cRDT positive = FP N = 32 27 (84.4) 11 (34.4) 8 (25.0)
cRDT negative = TN N = 57 16 (28.1) 9 (15.8) 0 (0)
uRDT positive = FP N = 41 33 (80.5) 12 (29.3) 8 (19.5)
uRDT negative = TN N = 48 10 (20.8) 8 (16.7) 0 (0)

TP True positive, FP false positive, TN true negative, FN false negative, HRP2 histidine-rich protein 2, pLDH Plasmodium lactate dehydrogenase, pLDH-Pan pan specific pLDH, pLDH-Pf P. falciparum specific pLDH