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. 2020 Dec 7;17:62. doi: 10.1186/s12989-020-00392-w

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Toxicity assessment of BEAS-2B cells exposed to CNT/F. a WST-1 cell proliferation assay was used to assess the viability of BEAS-2B cells following exposure to increasing concentrations (0.024–24 μg/ml) of CNT/F. The dose at which the particle significantly reduced cell viability is indicated with an asterisk (p < 0.05). b Oxidative stress was measured using the CellROX assay. * p < 0.05 fold change vs. control cells represented as a reference line. c Protein secretions from cells exposed to 2.4 or 24 μg/ml of various CNT/F for 24 h represented as heat maps of fold change from controls with no exposure.. Significant changes from control cells were indicated with an asterisk (* p < 0.05). Log fold change was represented by color with green indicating a decrease in protein concentration and red indicating an increase on a scale of − 0.2 to 1. (*p < 0.05)