Table 2.
Cohort baseline characteristics for comorbidities and Charlson comorbidity index
| Patient characteristics | POH MAP threshold | ||||
|---|---|---|---|---|---|
| Overall (n = 3185) |
≤ 55 mmHg (n = 654) |
≤ 65 mmHg (n = 1688) |
≤ 75 mmHg (n = 2674) |
> 75 mmHg (n = 511) |
|
| Comorbidities | |||||
| Myocardial infarction | 471 (14.8%) | 115 (17.6%) | 272 (16.1%) | 408 (15.3%) | 63 (12.3%) |
| Cerebrovascular accident | 1075 (33.8%) | 155 (23.7%) | 471 (27.9%) | 860 (32.2%) | 215 (42.1%) |
| COPD | 1157 (36.3%) | 284 (43.4%) | 657 (38.9%) | 1001 (37.4%) | 156 (30.5%) |
| Heart failure | 699 (22.0%) | 197 (30.1%) | 444 (26.3%) | 611 (22.9%) | 88 (17.2%) |
| Pulmonary circulatory disorder | 243 (7.6%) | 73 (11.2%) | 158 (9.4%) | 221 (8.3%) | 22 (4.3%) |
| Peripheral vascular disease | 656 (20.6%) | 171 (26.2%) | 395 (23.4%) | 578 (21.6%) | 78 (15.3%) |
| Hypertension | 2519 (76.0%) | 488 (74.6%) | 1270 (75.2%) | 2012 (75.2%) | 407 (79.7%) |
| Paralysis | 392 (12.3%) | 42 (6.4%) | 162 (9.60%) | 314 (11.7%) | 78 (15.3%) |
| Diabetes | 1099 (34.5%) | 224 (34.3%) | 581 (34.4%) | 927 (34.7%) | 172 (33.7%) |
| Hypothyroidism | 574 (18.0%) | 149 (22.8%) | 355 (21.0%) | 502 (18.8%) | 72 (14.1%) |
| Renal disease | 1170 (36.7%) | 286 (43.7%) | 681 (40.3%) | 1005 (37.6%) | 165 (32.3%) |
| Liver disease | 421 (13.2%) | 100 (15%) | 244 (14%) | 362 (14%) | 59 (12%) |
| Lymphoma | 42 (1.3%) | 12 (1.8%) | 21 (1.2%) | 34 (1.3%) | 8 (1.6%) |
| Solid tumor (local) | 949 (29.8%) | 207 (31.7%) | 524 (31.0%) | 825 (30.9%) | 124 (24.3%) |
| RA/ collagen vascular disease | 148 (4.7%) | 33 (5.1%) | 78 (4.6%) | 126 (4.7%) | 22 (4.3%) |
| Coagulopathy | 259 (8.1%) | 53 (8.1%) | 149 (8.8%) | 228 (8.5%) | 31 (6.1%) |
| Obesity | 714 (22.4%) | 148 (22.6%) | 363 (21.5%) | 600 (22.4%) | 114 (22.3%) |
| Anemia | 1801 (56.6%) | 436 (66.7%) | 1045 (61.9%) | 1564 (58.5%) | 237 (46.4%) |
| Alcohol abuse | 261 (8.2%) | 49 (7.5%) | 129 (7.6%) | 209 (7.8%) | 52 (10.2%) |
| Drug abuse | 249 (7.8%) | 43 (6.6%) | 103 (6.1%) | 198 (7.4%) | 51 (10.0%) |
| Smoking | 877 (27.5%) | 167 (25.5%) | 454 (26.9%) | 728 (27.2%) | 149 (29.2%) |
| Depression | 784 (24.6%) | 173 (26.5%) | 410 (24.3%) | 661 (24.7%) | 123 (24.1%) |
| Sleep apnea | 502 (15.8%) | 103 (15.8%) | 262 (15.5%) | 412 (15.4%) | 90 (17.6%) |
| Dementia | 154 (4.8%) | 36 (5.5%) | 93 (5.5%) | 131 (4.9%) | 23 (4.5%) |
| Chronic kidney disease* | 775 (24.3%) | 204 (31.2%) | 471 (27.9%) | 674 (25.2%) | 101 (19.8%) |
| Home oxygen | 178 (5.6%) | 44 (6.7%) | 112 (6.6%) | 161 (6.0%) | 17 (3.3%) |
| Right-side valve disease | 71 (2.2%) | 23 (3.5%) | 47 (2.8%) | 66 (2.5%) | 5 (1.0%) |
| Left-side valve disease | 135 (4.2%) | 41 (6.3%) | 92 (5.5%) | 122 (4.6%) | 13 (2.5%) |
| Charlson comorbidity index (CCI) | |||||
| 0 | 493 (15.5%) | 94 (14.4%) | 241 (14.3%) | 409 (15.3%) | 84 (16.4%) |
| 1 | 591 (18.6%) | 91 (13.9%) | 278 (16.5%) | 473 (17.7%) | 118 (23.1%) |
| 2 | 519 (16.3%) | 112 (17.1%) | 284 (16.8%) | 439 (16.4%) | 80 (15.7%) |
| 3 | 435 (13.7%) | 86 (13.2%) | 244 (14.5%) | 372 (13.9%) | 63 (12.3%) |
| ≥ 4 | 1147 (36.0%) | 271 (41.4%) | 641 (38.0%) | 981 (36.7%) | 166 (32.5%) |
Comorbidities and Charlson comorbidity index (CCI) for non-cardiac surgery patients discharged to the ICU after surgery without intraoperative hypotension (MAP ≤ 65 mmHg)
Due to rounding, categories will not always add to 100%. *This comorbidity was not used for model adjustment but was used to assess patient status and determine new onset of outcomes. POH, postoperative hypotension, MAP, mean arterial pressure; RA rheumatoid arthritis, COPD, Chronic Obstructive Pulmonary Disease