Fig. 6.

Effect of miR-219c-5p on the cell cycle and apoptosis in BSMCs. a Compared with that in the blank and NC groups, the number of BSMCs in the miR-219c-5p group increased in the G1 phase but decreased in the S/G2 phase, while the number of cells in the miR-219c-5p inhibition group decreased in the G1 phase but increased in the S/G2 phase (P < 0.05 in all cases). b The apoptosis rate of the miR-219c-5p group increased significantly compared with that of the blank and NC groups (P < 0.05). However, the apoptosis rate of the miR-219c-5p inhibition group was significantly reduced compared with that of the blank and NC groups (P < 0.05). The findings were from three independent experiments. The data are expressed as the means ± SD. *P < 0.05, **P < 0.01 versus mimic NC or inhibitor NC