Table 3.
Variable | EAE score | F Value | P Value | |||
---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | |||
Body weight/g | 27.99 ± 0.56 | 27.91 ± 0.78 | 25.81 ± 1.05 | 25.68 ± 0.87 | 0.5882 | 0.646 |
Bladder weight to total body weight (%) | 0.17 ± 0.01 | 0.20 ± 0.02 | 0.38 ± 0.02 | 0.56 ± 0.02 | 1002 | < 0.0001 |
FN1 | 1.00 ± 0.10 | 1.23 ± 0.70 | 1.59 ± 0.14 | 3.01 ± 0.10 | 342.7 | < 0.0001 |
miR-199a-3p | 3.40 ± 0.53 | 2.73 ± 0.25 | 1.93 ± 0.40 | 1.03 ± 0.15 | 23.6 | < 0.0001 |
miR-219c-5p | 3.10 ± 0.10 | 1.73 ± 0.08 | 1.23 ± 0.06 | 1.00 ± 0.10 | 376.4 | < 0.0001 |
miR-3572-3p | 4.50 ± 0.50 | 3.53 ± 0.55 | 2.03 ± 0.25 | 1.03 ± 0.15 | 44.6 | < 0.0002 |
Values are means ± SE; n = 3 mice/group. P < 0.05 by ANOVA among four groups; expression levels were normalized to β-actin or U6