Table 2. Frailty score [35, 82–84].
| Factors | Points |
|---|---|
| ≤ 75 years | 0 |
| 76–80 years | 1 |
| > 80 years | 2 |
| Activities of Daily Living (ADL)# | |
| > 4 | 0 |
| ≤ 4 | 1 |
| Instrumental Activities of Daily Living (IADL)## | |
| > 5 | 0 |
| ≤ 5 | 1 |
| Charlson Comorbidity Index (CCI)### | |
| ≤ 1 | 0 |
| ≥ 2 | 1 |
| Classification: | |
| Fit | 0 |
| Intermediate fitness | 1 |
| Frail | 2 to 5 |
| N = 869 (%) | SG 3 years (%) | SLP 3 years (%) | Nonhematological AEs, grade ≥ 3 (%) | Treatment discontinuity | Deaths |
| 39 | 84(s) | 48(s) | 22(s) | 17%(s) | 10% |
| 31 | 76(s) | 41(s) | 26(s) | 21%(s) | 14% |
| 30 | 57(s) | 33(s) | 34(s) | 31%(s) | 27% |
(s) = significant (p < 0.05) (bold). #Score (0 to 6) - 1 point: Bathing, dressing, using the toilet, transfer, continence and eating. ##Score (0 to 8) - 1 point: phoning, shopping, preparing food, taking care of the house, doing laundry, transportation, taking care of own medications, taking care of finances. ###Score (0 to 37) - 1 point: heart attack, heart failure, peripheral arterial disease, stroke, dementia, chronic obstructive pulmonary disease (COPD), collagenosis, peptic ulcer, mild liver disease, uninjured target-organ diabetes. 2 points: hemiplegia, at least moderate renal failure, injured target-organ diabetes, nonmetastatic cancer, leukemia, lymphoma. 3 points: at least moderate liver disease. 6 points: metastatic cancer, AIDS. Available online: http://www.myelomafrailtyscorecalculator.net/Geriatric.aspx.