Table 2. Principal Variations in Functional Parameters Before, During, and After the RRP.
| Variable | COVID Ward T0 (March 27) | COVID-Free Ward | |
|---|---|---|---|
| T1 (April 9) | T2 (April 21) | ||
| Blood samples | |||
| pH | 7.444 | 7.474 | 7.447 |
| Pao2, mm Hg | 79.9 | 76.3 | 84 |
| Paco2, mm Hg | 33.1 | 46.8 | 34.8 |
| Hb, g/dL | 10.5 | 9.1 | 8.9 |
| MV settings | |||
| Mode | PSV | np | np |
| PEEP, cm H2O | 8 | np | np |
| Fio2, % (activity) | 45 (45) | 24 (28) | 21 (21) |
| Pao2/Fio2 ratio | 177 | 246 | 400 |
| Respiratory function | |||
| BID | 61/100 | 9/100 | 0/100 |
| MIP/MEP, cm H2O (% predicted) | np | 68 (59)/83 (38) | 79 (68)/98 (45) |
| FEV1/FVC, % | np | np | 83.8 |
| FEV1, L (% predicted) | np | np | 2.49 (64) |
| FVC, L (% predicted) | np | np | 2.97 (60) |
| VC, L (% predicted) | np | np | 2.92 (59) |
| Functional capacity | |||
| BI | 19/100 | 99/100 | 100/100 |
| EQ-5D-3L12 | 12/15 | 6/15 | 5/15 |
| SPPB13 | 0/12 | 11/12 | 12/12 |
| Body composition and muscle strength | |||
| BMI, kg/m2 | 27.5 | 27.9 | 28.4 |
| MRC sum score4 | 48/60 | 52/60 | 58/60 |
| Q girth, cm (left/right) | 41.5/42 | 44/44 | 48/49 |
Abbreviations: BI, Barthel index; BID, Barthel index based on dyspnea; BMI, body mass index; COVID, coronavirus disease; EQ-5D-3L, EuroQol questionnaire—5 dimensions, 3 levels; FEV1, forced expired volume in the first second; Fio2, fraction of inspired oxygen; FVC, functional vital capacity; Hb, hemoglobin; MEP, maximal expiratory pressure; MIP, maximal inspiratory pressure; MRC sum score, Medical Research Council sum score; MV, mechanical ventilation; np, not performed; Pao2, arterial pressure of oxygen; Paco2, arterial pressure of carbon dioxide; PEEP, positive end-expiratory pressure; PVS, pressure ventilation support; Q girth, quadriceps size (taken 10 cm above patella); RRP, respiratory rehabilitation program; SPPB, Short Physical Performance Battery; VC, vital capacity.