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. 2020 Dec 10;77(1):147–157. doi: 10.1161/HYPERTENSIONAHA.120.16002

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© 2020 The Authors.

Hypertension is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.

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Figure 4. — Changes in expression of NMDA-NR1 (N-methyl-D-aspartate NR1 receptor) after Ang II infusion. A, NMDA-NR1 mRNA expression relative to rpl19 (ribosomal protein L 19) measured by real-time polymerase chain reaction in the (A) paraventricular nucleus of the hypothalamus (PVN) and (B) cortex of saline and Ang II-infused group. Changes in NMDA-NR1 mRNA are presented in folds with reference to the Saline group. C, Protein expression of NMDA-NR1 expression in the PVN (C) and (D) cortex of saline and Ang II-infused group top: a representative Western blot, bottom: densitometric analyses of NMDA-NR1 level normalized to tubulin. Values are mean±SEM (n=4–6 rats per group). T-test with Welch correction (A–D). *P=0.037 (A); P=0.396 (B); *P=0.035 (C); P=0.189 (D) vs saline control.