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. Author manuscript; available in PMC: 2020 Dec 7.
Published in final edited form as: J Clin Exp Immunol. 2020 Nov 23;5(6):252–258. doi: 10.33140/jcei.05.06.01

Table-1.

Cinnamon in autoimmune conditions

Autoimmune
conditions
Authors Finding Reference
number
Rheumatoid arthritis Rathi, B., et al. Oral polyphenolic fraction of Ceylon cinnamon protected arthritis in a rat model. 16
Rheumatoid arthritis Cheng, W., X. et al. Oral cinnamaldehyde protected rats from collagen-induced arthritic rats. 17
Rheumatoid arthritis Shishehbor, F., et al. Oral cinnamon reduced disease severity in women with rheumatoid arthritis 18
Type 1 diabetes Shen, Y., et al. Ceylon cinnamon exhibited anti-diabetic effect in insulin-uncontrolled type 1 diabetic rats 24
Type 1 diabetes Altschuler, J. A., et al. Oral cinnamon did not show significant anti-diabetic effect in adolescent TIDM patients. 25
Type 1 diabetes Baker, W. L., et al. Upon meta-analysis of prospective randomized controlled trials, cinnamon did not display anti-diabetic effect. 26
Multiple sclerosis Brahmachari, S., et al. Sodium benzoate, a metabolite of cinnamon, exhibited protection in a mouse model of MS. 14
Multiple sclerosis Mondal, S., et al. Oral cinnamon displayed protection in three different animal models of MS. 12
Inflammatory bowel disease Kwon, H.K., et al. Oral cinnamon extract protected mice from intestinal colitis. 38
Inflammatory bowel disease Hagenlocher, Y., et al. Cinnamaldehyde decreased fibrotic symptoms and markers in a mouse model of colitis. 39
Inflammatory bowel disease Hagenlocher, Y., et al. Oral cinnamon extract reduces murine colitis in IL-10−/− mice. 40
Inflammatory bowel disease Li, A.L., et al. Cinnamon essential oil protected mice from dextran sodium sulfate-induced colitis. 41