. Author manuscript; available in PMC: 2021 Dec 8.

Published in final edited form as: J Am Coll Cardiol. 2020 Dec 8;76(23):2755–2763. doi: 10.1016/j.jacc.2020.10.003

Table 4:

Comparison of Endothelial and End-organ Function Indices

	All (n=29)	mPAP/CO lope >3
	All (n=29)	No (n=8)	Yes (n=12)	p
Endothelial function
EndoPAT-derived RHI	1.1 (0.2–4.2)	1.5 (0.6–4.2)	0.9 (0.2–2.5)	<0.001
LnRHI	0.22±0.17	0.27±0.11	0.20±0.11	<0.001
End-organ function
MRE liver stiffness, kPa	5.6±1.8	4.9±0.8	5.8±0.6	0.03
GFR, ml/min/1.73 m²	86±11	98±8	77±6	0.02
NT-proBNP, pg/ml	461±128	314±66	502±102	0.01
Estimated plasma volume, ml	3,181 ±613	2,284±207	3,301±422	0.07
Peak VO₂ ,% predicted	56±18	67±11	49±15	<0.001
MLHFQ	39±22	24±15	42±13	0.004

RHI: reactive hyperemia index; LnRHI: natural log of reactive hyperemia index; MRE: magnetic resonance elastography; GFR: glomerular filtration rate; NT proBNP: N-terminal pro hormone brain natriuretic peptide; VO₂: oxygen consumption; MLHFQ: Minnesota living with heart failure questionnaire; mPAP/CO slope: slope of mean pulmonary artery pressure versus cardiac output