Table 3.
The collagen gel droplet-embedded culture drug sensitivity test of different chemotherapy drugs in primary cells
| Chemotherapy drug | Total | Molecular subtype |
χ2 | P | |||
|---|---|---|---|---|---|---|---|
| Luminal A (%) | Luminal B (%) | HER2+ (%) | Basal-like (%) | ||||
| Paclitaxel | 8.626 | 0.035* | |||||
| + | 93 | 40 (54.8) | 8 (11.0) | 12 (16.4) | 33 (45.2) | ||
| – | 128 | 76 (59.4) | 14 (10.9) | 13 (10.2) | 25 (19.5) | ||
| Epirubicin | 16.973 | 0.001* | |||||
| + | 90 | 37 (41.1) | 8 (8.9) | 18 (20.0) | 27 (30.0) | ||
| – | 134 | 81 (60.4) | 15 (11.2) | 6 (4.5) | 32 (28.9) | ||
| Carboplatin | 7.732 | ||||||
| + | 62 | 30 (48.4) | 2 (3.2) | 9 (14.5) | 21 (33.9) | ||
| – | 142 | 79 (55.6) | 18 (12.7) | 15 (10.6) | 30 (21.1) | 0.052 | |
| Vinorelbine | 1.958 | ||||||
| + | 46 | 28 (60.9) | 4 (8.7) | 5 (10.9) | 9 (19.6) | ||
| – | 164 | 82 (50.0) | 17 (10.4) | 19 (11.6) | 46 (28.0) | 0.581 | |
| Fluorouracil | 4.384 | ||||||
| + | 33 | 20 (60.6) | 1 (3.0) | 3 (9.1) | 9 (27.3) | ||
| – | 104 | 50 (48.1) | 15 (14.4) | 10 (9.6) | 29 (27.9) | 0.223 | |
*P < 0.05.