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. 2020 Dec 15;17(4):1002–1013. doi: 10.20892/j.issn.2095-3941.2020.0089

Figure 3.

Figure 3

Mutations in HR genes are associated with tumor aneuploidy and tumor immunogenicity. (A, D) HR-mut GC (A) and BRCA1/2-mut GC (D) had significantly lower copy number variation burden scores than the corresponding wt groups. (B, E) The LOH fraction is significantly smaller in HR-mut GC (B) and BRCA1/2-mut GC (E) than in the corresponding wt groups. (C, F) Immunogenic mutations are significantly higher in HR-mut GC (C) and BRCA1/2-mut GC (F) than in the corresponding wt groups. P-values were calculated with the Wilcoxon test; the box shows the upper and lower quartiles (*P < 0.05, **P < 0.01, ***P < 0.001).