Table 2.
Medications Taken at Baseline in the Alpha Lipoic Acid Groups
| Dose, mg Patients, n |
400 83 |
600 78 |
800 80 |
1200 81 |
|---|---|---|---|---|
| Antihypertensives, n (%) | ||||
| Diuretic | 8 (10.1) | 6 (8.3) | 5 (7.0) | 9 (12.0) |
| ACE-I | 11 (13.9) | 10 (13.9) | 9 (12.7) | 12 (16.0) |
| Sartan | 9 (11.4) | 13 (18.1) | 8 (11.3) | 10 (13.3) |
| Ca-antagonist | 7 (8.9) | 6 (8.3) | 8 (11.3) | 7 (9.3) |
| β-blocker | 3 (3.8) | 2 (2.8) | 2 (2.8) | 3 (4.0) |
| Hypocholesterolemics, n (%) | ||||
| Statin | 16 (20.3) | 15 (20.8) | 13 (18.3) | 18 (24.0) |
| Fibrate | 5 (6.3) | 4 (5.6) | 4 (5.6) | 6 (8.0) |
| Ezetimibe | 6 (7.6) | 7 (9.7) | 9 (12.7) | 7 (9.3) |
| Omega-3 | 4 (5.1) | 5 (5.6) | 4 (5.6) | 2 (2.7) |
| PCSK9-I | 3 (3.8) | 2 (2.8) | 1 (1.4) | 1 (1.3) |
| Antiarrhythmics, n (%) | ||||
| Amiodarone | 2 (2.5) | 1 (1.4) | 0 | 0 |
| Digoxin | 1 (1.3) | 0 | 1 (1.4) | 0 |
| PPI, n (%) | ||||
| Omeprazole | 3 (3.8) | 4 (5.6) | 2 (2.8) | 1 (1.3) |
| Pantoprazole | 2 (2.5) | 1 (1.4) | 0 | 0 |
| Antiaggregants, n (%) | ||||
| ASA | 3 (3.8) | 4 (5.6) | 2 (2.8) | 1 (1.3) |
| Clopidogrel | 2 (2.5) | 1 (1.4) | 0 | 0 |
Notes: n, number of patients; %, percentage of patients.
Abbreviations: ACE-I, angiotensin-converting enzyme-inhibitors; PCSK9-I, proprotein convertase subtilisin/kexin type 9-inhibitors; PPI, proton pump inhibitors; ASA, acetylsalicylic acid.