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. 2020 Dec 7;15(12):e0243493. doi: 10.1371/journal.pone.0243493

Table 2. Phenotyping drug resistance profiles for first-line drugs among confirmed EPTB patients by patient history profile, 2020.

Drug resistance pattern Isolates from new cases, n (%) Isolates from previously treated cases, n % Total n (%)
Total tested Isolate 137 14 151
Susceptible 115(83.9) 7(50.0) 122(80.8)
Resistance to any drug
STM 7(5.1) 2(14.2) 9 (6.0)
INH 19(13.8) 3(21.4) 22 (14.6)
RIF 11(8.0) 3(21.4) 14 (9.3)
EMB 3(2.2) - 3 (2.0)
PZA 19(13.9) 3(21.4) 22(14.6)
Mono resistance
INH 2(1.5) 1(7.1) 3 (2.0)
PZA 8(5.8) 1(7.1) 9(5.9)
Resistance to more than one drug
INH + RIF 11(8.0) 3(21.4) 14(9.3)
INH + PZA 12(8.6) 3(21.4) 15(9.9)
INH + STM 7(5.1) 2(14.3) 9(6.0)
INH + EMB 3(2.2) - 3(1.32)
INH + RIF + STM 4(2.9) 1(7.1) 5(3.3)
INH + RIF + EMB 2(1.5) - 2(1.3)
INH + RIF + PZA 8(5.8) 2(14.3) 10(6.6)
INH + RIF + EMB + PZA 1(0.7) - 1(0.7)
STM + INH + RIF + PZA 4(2.9) 1(7.1) 5(3.3)
INH + RIF or MDR 11(8.0) 3(21.4) 14 (9.3)

STM-Streptomycin, INH-Isoniazid, RIF-Rifampicin, EMB-Ethambutol, PZA-Pyrazinamide, MDR-Multi drug resistance.