Fig 1. Islet recovery after 7 days of tissue culture in control media (—) or media supplemented with 4 different doses of necrostatin-1 (25, 50, 100, or 200 μM of Nec-1) on day 3.

Islet recovery was calculated by normalizing the islet equivalents of all groups on day 7 to day 3 before Nec-1 supplementation (dotted line) and expressed as percentage. n = 6 for each group. ^#p < .05 vs day 3. ^##p < .01 vs day 3. *p < .05. **p < .01. Data are expressed as mean ± SEM.