TABLE 1.
Demographics and baseline clinical variables
| HIV infected (n = 42) | HC (n = 46) | p‐Value | |
|---|---|---|---|
| Age (years) mean ± SE | 34.9 ± 2.2 | 37.3 ± 2.1 | .196 |
| Gender (male:female) | 39:3 | 23:23 | <.001 |
| Ethnicity (White:Black:Other) | 22:19:1 | 35:5:6 | .042 |
| Education | |||
| ≤12 years | 12 | 6 | 1 |
| >12 years | 30 | 40 | |
| HIV duration by patient report at baseline (months) median (lower quantile, upper quantile) | 1 (1, 12.75) | NA | — |
| Baseline CD4 cell count (cells/mm3) mean ± SE | 515.8 ± 42.3 | NA | — |
| Baseline HIV RNA levels (log10 unit) median (range) | 4.5 (1.7, 5.8) | NA | — |
| HAND classification at baseline | |||
| Normal | 21 | NA | 1 |
| ANI | 20 | NA | |
| MND | 1 | NA | |
| Total NPZ score mean (SD) | |||
| BSL | −1.886 (3.79) | 0.100 (3.94) | .014 |
| 12 week | −0.187 (3.88) | — | |
Abbreviations: 12‐week, HIV+ after 12‐weeek cART treatment; ANI, asymptomatic neurocognitive impairment; BSL, HIV+ and HC at baseline; CD4, cluster of differentiation 4; HAND, HIV‐associated neurocognitive disorder; HC, healthy control; MND, mild neurocognitive disorder; NPZ score, neuropsychological test Z‐score; SE, standard error.