Figure 8.

Schematic diagram of material synthesis. (A) Schematic of the hierarchical structure of LbL films into a single coating. The first (X) film is a hydrolytically degradable undercoating, while the second (Y) film contains the siRNA to be delivered. (B) Side-on schematic of hierarchical LBL film architecture. Reprinted with permission from Castleberry SA, Almquist BD, Li W, et al. Self-assembled wounddressings silenceMMP-9 and improve diabetic wound healing in vivo. Adv Mater. 2016;28:1809–1817. Copyright 2016, John Wiley and Sons.⁷⁹ (C) Schematic illustration of the synthesis procedure and rESW-responsive oxygen release from Nano-PFC. Adapted from Wang S, Yin C, Han X, et al. Improved healing of diabetic footulcer upon oxygenation therapeutics through oxygen-loading nanoperfluorocarbontriggered by radial extracorporeal shock wave. Oxid Med Cell Longev. 2019;2019:5738368. Creative Commons license and disclaimer available from: http://creativecommons.org/licenses/by/4.0/legalcode.¹⁸⁹