Table 1.
List of 14 anxiety-associated proteins–targets of PPARs.
| Protein | Full name | Functional class | PPARs |
|---|---|---|---|
| BDNF | Brain derived neurotrophic factor | Growth factor | PPARA PPARG |
|
| |||
| CREB1 | cAMP responsive element binding protein 1 | Class bZIP transcription factor | PPARA PPARG |
|
| |||
| CRP | C-reactive protein | Plasma protein | PPARA PPARG |
|
| |||
| FOS | FOS proto-oncogene, AP-1 transcription factor subunit | Class bZIP transcription factor | PPARA PPARG |
|
| |||
| HSD11B2 | Hydroxysteroid 11-beta dehydrogenase 2 | Steroid metabolism protein | PPARD |
|
| |||
| IFNG | Interferon gamma | Inflammatory cytokine | PPARA PPARD PPARG |
|
| |||
| IL6 | Interleukin 6 | Inflammatory cytokine | PPARA PPARD PPARG |
|
| |||
| LEP | Leptin | Adipokine | PPARD PPARG |
|
| |||
| NPY | Neuropeptide Y | Neuropeptide | PPARG |
|
| |||
| NR3C1 | Nuclear receptor subfamily 3 group C member 1 | Nuclear steroid hormone receptor family | PPARA |
|
| |||
| PRL | Prolactin | Glycopeptide hormone (gonadotropins) | PPARA |
|
| |||
| TNF | Tumor necrosis factor | Inflammatory cytokine/adipokine | PPARA PPARD PPARG |
|
| |||
| TSPO | Translocator protein | Mitochondrial damage protein | PPARA |
|
| |||
| VEGFA | Vascular endothelial growth factor A | Growth factor | PPARA PPARD PPARG |