Table 2. Known function of genes under selection in sheep1).
| Trait class | Trait | Gene |
|---|---|---|
| Growth and development | Body weight | GHR, MB, LEPR, GHRHR, CAST |
| Average daily gain | LEPR | |
| Shin circumference | MB | |
| Curd firmness | FAS, LALBA | |
| Reproduction | Litter size | FSHR, GHR, MB |
| Age at first lambing | MB | |
| Teat number | MB | |
| Interval between first and second lambing | MB | |
| Age at puberty | LEPR | |
| Testes weight | TGFB1 | |
| Carcass and meat quality | Backfat at 12th/13th ribs | GHR, GHRHR, CAST |
| Backfat at third lumbar | MB | |
| Carcass length | GHR | |
| Hot carcass weight | GHR | |
| Lumbar vertebra number | MB | |
| Lumbar weight | MB | |
| Subcutaneous fat thickness | MB | |
| Muscle depth at third lumbar | MB, ACACA | |
| Tail fat deposition | MB | |
| Abdominal fat weight | GHR | |
| Longissimus muscle area | SCD5 | |
| Milk | Yield | MB |
| Curd firming time | FAS, LALBA | |
| Composition | GHR, MB, GHRHR, FAS, ITGB1, IGF1, ACACA, TGFB1, STAT5A | |
| Fiber quality | Greasy fleece weight | MB |
| Mean fiber diameter | MB, FST | |
| Fiber diameter coefficient of variance | MB, FST | |
| Fiber diameter standard deviation | MB, FST | |
| Wool crimp | FST | |
| Staple length | TGFB1 | |
| Health | Haemonchus contortus resistance | MB |
| Fecal egg count | MB | |
| Maedi-Visna virus susceptibility | MB, TMEM154 | |
| Pneumonia susceptibility | MB, KCNMA1, IL6 | |
| Facial eczema susceptibility | MB | |
| Scrapie susceptibility | MB |
1)
This table is based on the information searched in Animal QTLdb (accessed April 22, 2020) database.
GHR, growth hormone receptor; MB, myoglobin; LEP, leptin receptor; GHRHR, growth hormone releasing hormone receptor; CAST, calpastatin; FAS, Fas cell surface death receptor; LALBA, lactalbumin alpha; FSHR, follicle stimulating hormone receptor; TGFB1, transforming growth factor beta 1; ACACA, acetyl-CoA carboxylase alpha; SCD5, stearoyl-CoA desaturase 5; ITGB1, integrin subunit beta 1; IGF1, insulin like growth factor 1; STAT5A, signal transducer and activator of transcription 5A; FST, follistatin; KCNMA1, potassium calcium-activated channel subfamily M alpha 1; IL6, interleukin 6.