Table 4.

ATP synthase inhibition for representative compounds of Table 1.

No	M. smeg ATPsyntha	Mamm. ATPsyntha
1	0.55	>1000
6	5.5	23
8	4.2	16
10	7.2	>500
23	6.2	>500
26	14	13
27	2.2	7.2
35	6.3	20
36	3.0	27
42	1.8	17
49	6.2	48

^aIC₅₀ values (µg/mL) for inhibition of M. smegmatis and human mitochondrial ATP synthase.²²