Figure 2.

ABA inhibits cell proliferation and regulates cell cycle markers in PCa cells. (A) PCa cell proliferation assays were performed in 1% FBS culture condition with ABA treatment. (B) PCa cell cytotoxicity assays were performed in 10% FBS culture condition with 4 h of the ABA treatment. Data in Figure 1A, B are representative of mean with SD (Student's t test). *, P < 0.001 to 0.01. mRNA expression levels of (C) p27, (D) p21, (E) p16, and (F) Ki67 were measured in PCa cells with vehicle or ABA (50 µM) treatment by real-time PCR. Data in C-F are representative of mean with SD (Student's t test).