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. 2020 Dec 7;10:21321. doi: 10.1038/s41598-020-78441-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Autochthonous intestinal microbiota from sea bass Dicentrarchus labrax fed with control diet (D0) and different doses of microencapsulated OA and NIC (D250, D500 and D1000). (A) Average phylogenetic profiles of the gut microbiome of sea bass are provided at phylum (left) and genus (right) level; Phyla and genus which represent < 1.5% of the autochthonous community were included in ‘Others’. (B) Principal Component Analysis (PCA) of the Euclidean distance of sea bass gut microbial ecosystem after the assumption of different diets (D0, D250, D500 and D1000). A significant separation among groups was observed [P value = 0.03; Permutation test with pseudo-F ratios (Adonis)]. (C) Alpha diversity of the sea bass GM for all diet assumption was estimated with observed species and Shannon metrics.