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. 2020 Dec 7;10:21321. doi: 10.1038/s41598-020-78441-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Profile of putative functions encoded by the sea bass gut microbial community during the diet intervention (D0, D250, D500, D1000). Principal Component Analysis (PCA) based on Euclidean distance between samples is reported in (A). A significant separation among groups was observed [P value = 0.04—Permutation test with pseudo-F ratios (Adonis)]. (B) D1000 promotes a significant decrease in several inflammation-promoting and homeostatic functions, such as bacterial invasion of epithelial cells (P = 0.01—Wilcoxon rank-sum test), bacterial toxins (P = 0.01—Wilcoxon rank-sum test) and mineral absorption (P = 0.02—Wilcoxon rank-sum test).