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. 2020 Dec 7;10:21367. doi: 10.1038/s41598-020-78374-3

Table 3.

The intra-test discordance and concordance of serial QuantiFERON-TB Gold Plus (QFT-Plus) and QuantiFERON-TB Gold In-tube (QFT-GIT) tests, respectively.

(A)
1st QFT-Plus(−)
(n = 20)
1st QFT-Plus(+)
(n = 33)
2nd QFT-Plus(−) 16 (80%) 6 (12.9%)
2nd QFT-Plus(+) 4 (20%) 27 (81.8%)*
Persistent positive rate: 81.8%
Cohen’s kappa value: 0.61
(B)
1st QFT-GIT(−)
(n = 19)
1st QFT-GIT(+)
(n = 34)
2nd QFT-GIT(−) 15 (78.9%) 14 (41.2%)
2nd QFT-GIT(+) 4 (21.1%) 20 (58.8%)*
Persistent positive rate: 58.8%
Cohen’s kappa value: 0.34

*p = 0.040 by comparing persistent positivity between the 1st and 2nd QFT-GIT(+) versus the 1st and 2nd QFT-Plus(+) using Pearson chi-squared test.