Table 4.
Demographic data between persistent positive result or negative reversion groups of QFT-GIT and QFT-Plus.
| 1st QFT-GIT(+) 2nd QFT-GIT(+) (n = 20) |
1st QFT-GIT(+) 2nd QFT-GIT(−) (n = 14) |
p | 1st QFT-Plus(+) 2nd QFT-Plus(+) (n = 27) |
1st QFT-Plus(+) 2nd QFT-Plus(−) (n = 6) |
p | |
|---|---|---|---|---|---|---|
| Age | 57.7 ± 12.2 | 55.8 ± 10.7 | 0.631 | 55.9 ± 12.2 | 61.3 ± 10.4 | |
| Sex, male n (%) | 15 (75) | 10 (71) | 1 | 21 (78) | 2 (33) | 0.053 |
| Dialysis (HD) n (%) | 13 (65) | 9 (64) | 1 | 19 (70) | 5 (83) | 1 |
| DM, n (%) | 6 (30) | 3 (21) | 0.704 | 8 (30) | 2 (33) | 1 |
| Previous TB n (%) | 0 | 0 | NA | 1 (4) | 0 | NA |
| BCG scar n (%) | 16 (80) | 13 (93) | 0.379 | 21 (78) | 6 (100) | 0.563 |
| LTBI treatment n (%) | 17 (85) | 10 (71) | 0.410 | 19 (70) | 6 (100) | 0.160 |
| QFT-GIT0* | 2.47 ± 0.55 | 1.20 ± 0.81 | < 0.001 | 2.25 ± 0.43 | 2.86 ± 3.56 | 0.924 |
| QFT-GIT1* | 2.80 ± 2.37 | 0.98 ± 0.81 | < 0.001 | 2.39 ± 2.22 | 0.63 ± 0.21 | < 0.001 |
| QFT-Plus1 | ||||||
| T1 of QFT-Plus1* | 2.32 ± 2.15 | 0.80 ± 0.98 | 0.010 | 2.13 ± 1.96 | 0.55 ± 0.30 | < 0.001 |
| T2 of QFT-Plus1* | 2.43 ± 2.18 | 0.95 ± 1.26 | 0.018 | 2.27 ± 2.01 | 0.62 ± 0.28 | < 0.001 |
| T2–T1 of QFT-Plus1* | 0.11 ± 0.56 | 0.15 ± 0.37 | 0.804 | 0.14 ± 0.59 | 0.08 ± 0.06 | 0.563 |
| QFT-GIT2* | 2.17 ± 1.66 | 0.18 ± 0.09 | < 0.001 | 1.67 ± 1.63 | 0.05 ± 0.14 | < 0.001 |
| QFT-Plus2* | ||||||
| T1 of QFT-Plus2* | 1.63 ± 1.35 | 0.18 ± 0.21 | < 0.001 | 1.31 ± 1.27 | 0.02 ± 0.13 | < 0.001 |
| T2 of QFT-Plus2* | 1.39 ± 0.82 | 0.19 ± 0.17 | < 0.001 | 1.10 ± 0.77 | − 0.01 ± 0.23 | < 0.001 |
| T2–T1 of QFT-Plus2* | − 0.24 ± 0.78 | 0.01 ± 0.11 | 0.163 | − 0.21 ± 0.65 | − 0.02 ± 0.17 | 0.213 |
QFT-GIT response: the interferon-gamma level of the TB antigen tube minus the negative control in the QFT-GIT test. The unit is IU/ml.
T1/T2 of QFT-Plus: the interferon-gamma level of the TB1 or TB2 tube minus the negative control in the QFT-Plus test. The unit is IU/ml.
T2–T1 of QFT-Plus1: the level of the T2 tube minus the T1 tube in the QFT-Plus test. The unit is IU/ml.
*Subscripts: 0, the baseline test; 1, the 1st follow-up; 2, the 2nd follow-up.
BCG, Bacillus Calmette-Guérin vaccine; DM: Diabetes mellitus; F, female; HD, Hemodialysis; LTBI, latent tuberculosis infection; M, male; NA, non-applicable; QFT-GIT: QuantiFERON-TB Gold In-tube; QFT-Plus: QuantiFERON-TB Gold Plus; TB, tuberculosis.