Table 1.

Cytokines analysis of maternal organs and E18 microglia.

	E12 Ctrl	E12 MIA	P	N	E15 Ctrl	E15 MIA	P	N
Liver
IL-6	1.0 ± 0.045	2.3 ± 0.82	0.021	4 vs. 4	1.0 ± 0.35	4.6 ± 2.7	0.038	4 vs. 4
IL-1β	0.97 × 10−4 ± 0.75 × 10−4	0.55 × 10−4 ± 0.79 × 10−4	0.54	3 vs. 3	0.46 × 10−4 ± 0.56 × 10−4	2.0 × 10−4 ± 2.0 × 10−4	0.26	3 vs. 3
TNFα	0.0 ± 0.0	0.39 × 10−5 ± 0.42 × 10−5	0.18	3 vs. 3	0.0 ± 0.0	0.22 × 10−5 ± 0.33 × 10−5	0.28	3 vs. 3
IL-17a	0.0 ± 0.0	1.10 × 10−4 ± 1.2 × 10−4	0.18	3 vs. 3	0.0 ± 0.0	0.30 × 10−6 ± 0.43 × 10−6	0.30	3 vs. 3
CD68	0.23 × 10−3 ± 0.13 × 10−3	0.16 × 10−3 ± 0.15 × 10−3	0.56	3 vs. 3	0.081 × 10−3 ± 0.14 × 10−3	0.64 × 10−3 ± 0.59 × 10−3	0.19	3 vs. 3
ICAM-1	0.35 × 10−2 ± 0.12 × 10−2	0.33 × 10−2 ± 0.13 × 10−2	0.85	3 vs. 3	0.34 × 10−2 ± 0.49 × 10−3	0.61 × 10−2 ± 0.25 × 10−2	0.14	3 vs. 3
Placenta
IL-6	1.0 ± 0.40	2.8 ± 1.9	0.049	6 vs. 6	1.0 ± 0.28	14.6 ± 12.0	0.019	6 vs. 6
IL-1β	0.33 × 10−4 ± 0.22 × 10−4	0.99 × 10−4 ± 0.42 × 10−4	0.075	3 vs. 3	0.84 × 10−4 ± 0.35 × 10−4	0.94 × 10−4 ± 0.30 × 10−4	0.72	3 vs. 3
TNFα	0.31 × 10−4 ± 0.41 × 10−4	0.68 × 10−4 ± 0.43 × 10−4	0.34	3 vs. 3	0.88 × 10−4 ± 0.57 × 10−5	0.42 × 10−4 ± 0.48 × 10−4	0.17	3 vs. 3
IL-17a	0.70 × 10−6 ± 1.0 × 10−6	0.38 × 10−6 ± 0.39 × 10−6	0.70	3 vs. 3	1.1 × 10−6 ± 1.6 × 10−6	1.2 × 10−6 ± 1.1 × 10−6	0.97	3 vs. 3
CD68	0.20 ± 0.085	0.22 ± 0.050	0.70	3 vs. 3	0.16 ± 0.14	0.17 ± 0.060	0.90	3 vs. 3
ICAM-1	0.59 × 10−3 ± 0.50 × 10−3	1.08 × 10−3 ± 0.27 × 10−3	0.21	3 vs. 3	0.84 × 10−3 ± 0.76 × 10−3	1.5 × 10−3 ± 0.44 × 10−3	0.29	3 vs. 3
Brain
IL-6	1.0 ± 0.16	1.5 ± 0.35	0.090	3 vs. 3	0.33 ± 0.58	1.37 ± 2.3	0.49	3 vs. 3
IL-1β	0.45 × 10−5 ± 0.42 × 10−5	1.1 × 10−5 ± 1.6 × 10−5	0.51	3 vs. 3	1.0 × 10−5 ± 0.42 × 10−5	1.7 × 10−5 ± 1.2 × 10−5	0.39	3 vs. 3
TNFα	0.49 × 10−5 ± 0.79 × 10−5	0.97 × 10−6 ± 0.84 × 10−6	0.44	3 vs. 3	0.54 × 10−6 ± 0.53 × 10−6	0.59 × 10−6 ± 0.53 × 10−6	0.91	3 vs. 3
IL-17a	0.15 × 10−5 ± 0.17 × 10−5	0.18 × 10−5 ± 0.30 × 10−5	0.85	3 vs. 3	0.15 × 10−6 ± 0.10 × 10−6	0.35 × 10−6 ± 0.13 × 10−6	0.11	3 vs. 3
CD68	5.2 × 10−3 ± 0.73 × 10−3	5.6 × 10−3 ± 0.46 × 10−3	0.48	3 vs. 3	5.5 × 10−3 ± 0.54 × 10−3	7.0 × 10−3 ± 0.29 × 10−3	0.016	3 vs. 3
ICAM-1	2.3 × 10−4 ± 0.34 × 10−4	1.9 × 10−4 ± 0.70 × 10−4	0.49	3 vs. 3	3.3 × 10−4 ± 1.1 × 10−4	3.6 × 10−4 ± 0.68 × 10−4	0.73	3 vs. 3
E18 microglia
IL-6	1.0 ± 0.44	8.9 ± 6.5	0.040	5 vs. 5 (5 pooled embryos from 5 mice)	1.0 ± 0.61	3.6 ± 1.9	0.028	4 vs. 4 (4 pooled embryos from 4 mice)
IL-1β	1.0 ± 0.42	1.2 ± 0.90	0.60	5 vs. 5 (5 pooled embryos from 5 mice)	1.0 ± 0.57	26 ± 8.5	0.0021	4 vs. 4 (4 pooled embryos from 4 mice)
TNFα	1.0 ± 0.38	0.31 ± 0.11	0.0078	5 vs. 5 (5 pooled embryos from 5 mice)	1.0 ± 0.10	3.1 ± 3.6	0.30	4 vs. 4 (4 pooled embryos from 4 mice)
IL-17a	0.10 × 10−7 ± 0.16 × 10−7	0.56 × 10−7 ± 0.71 × 10−7	0.26	4 vs. 4 (4 pooled embryos from 2 mice)	0.090 × 10−7 ± 0.18 × 10−7	0.90 × 10−7 ± 1.6 × 10−7	0.34	4 vs. 4 (4 pooled embryos from 2 mice)
CD68	0.18 ± 0.025	0.19 ± 0.033	0.62	4 vs. 4 (4 pooled embryos from 2 mice)	0.19 ± 0.048	0.16 ± 0.054	0.44	4 vs. 4 (4 pooled embryos from 2 mice)
ICAM-1	1.1 × 10−2 ± 0.21 × 10−2	1.2 × 10−2 ± 0.34 × 10−2	0.48	4 vs. 4 (4 pooled embryos from 2 mice)	0.94 × 10−2 ± 0.17 × 10−2	0.80 × 10−2 ± 0.19 × 10−2	0.31	4 vs. 4 (4 pooled embryos from 2 mice)