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. 2020 Dec 7;10:21378. doi: 10.1038/s41598-020-78294-2

Table 7.

Morphological analysis of P42 microglia with and without LPS application.

E12 Ctrl
LPS, P value	Before	After	P value	Before	After	P value
	Soma area (μm²)			Total process length (μm)
Mean ± SD	39.5 ± 5.54	45.8 ± 7.69	0.0003	203 ± 31.0	170 ± 37.2	< 0.0001
Number of cells	12 (from 4 mice)	12 (from 4 mice)	0.0003	12 (from 4 mice)	12 (from 4 mice)	< 0.0001
	Number of processes			Number of branches
Mean ± SD	5.08 ± 0.67	5.00 ± 0.60	0.34	14.1 ± 2.58	11.5 ± 3.37	0.0001
Number of cells	12 (from 4 mice)	12 (from 4 mice)	0.34	12 (from 4 mice)	12 (from 4 mice)	0.0001

E12 MIA
LPS, P value	Before	After	P value	Before	After	P value
	Soma area (μm²)			Total process length (μm)
Mean ± SD	40.4 ± 10.0	46.9 ± 11.9	0.0005	217 ± 35.7	177 ± 30.1	0.0001
Number of cells	12 (from 4 mice)	12 (from 4 mice)	0.0005	12 (from 4 mice)	12 (from 4 mice)	0.0001
	Number of processes			Number of branches
Mean ± SD	4.67 ± 0.49	4.58 ± 0.52	0.34	15.0 ± 2.05	11.9 ± 2.81	< 0.0001
Number of cells	12 (from 4 mice)	12 (from 4 mice)	0.34	12 (from 4 mice)	12 (from 4 mice)	< 0.0001

E15 MIA
LPS, P value	Before	After	P value	Before	After	P value
	Soma area (μm²)			Total process length (μm)
Mean ± SD	39.8 ± 3.80	47.0 ± 5.25	0.0011	211 ± 40.0	168 ± 29.2	< 0.0001
Number of cells	12 (from 4 mice)	12 (from 4 mice)		12 (from 4 mice)	12 (from 4 mice)
	Number of processes			Number of branches
Mean ± SD	4.75 ± 0.62	4.67 ± 0.49	0.59	15.0 ± 2.13	11.5 ± 1.83	0.0009
Number of cells	12 (from 4 mice)	12 (from 4 mice)		12 (from 4 mice)	12 (from 4 mice)