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. 2020 Dec 7;11(12):1038. doi: 10.1038/s41419-020-03240-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — A Wander tool analysis for the degree of PlncRNA-1 promoter methylation in BC tissues. B MEXPRESS tool analysis for the relationship between the degree of PlncRNA-1 promoter methylation and its expression level in BC. C, D BSAS analysis for the degree of PlncRNA-1 promoter region methylation. E, F The effect of AZA treatment on the methylation level of PlncRNA-1 promoter at position 131. The red peak represents the base T, which is unmethylated. The blue peak represents the base C, which is methylated. Black dots represent methylation, whereas white ones represent unmethylation. G The expression level of PlncRNA-1 after treatment of BC cells with varied AZA concentrations. H Degree of PlncRNA-1 promoter region methylation in BC tissues. I The expression level of PlncRNA-1 in six pairs of normal and BC tissues.