Table 1.
MICs of T405, imipenem and faropenem tested against the reference strain (ATCC 19977) and 20 clinical strains of M. abscessus in vitro.
| Isolate # | T405 | Imipenem | Faropenem |
|---|---|---|---|
| MIC (μg/ml) | |||
| ATCC 19977 | 2 | 8 | 512 |
| 1N | 2 | 8 | 256 |
| 2N | 2 | 8 | 256 |
| 3N | 2 | 8 | 256 |
| 4N | 1 | 16 | 256 |
| 5N | 1 | 16 | 512 |
| 11N | 8 | 32 | 512 |
| 13N | 1 | 8 | 64 |
| 14N | 8 | 32 | 512 |
| 202 | 2 | 16 | 512 |
| 203 | 2 | 32 | 128 |
| 204 | 8 | 32 | 512 |
| 214 | 1 | 8 | 128 |
| 215 | 2 | 16 | 512 |
| JHH2 | 4 | 32 | 512 |
| JHH4 | 2 | 16 | 512 |
| JHH9 | 4 | 16 | 512 |
| 8N | 4 | 32 | 512 |
| JHHKB | 2 | 256 | 512 |
| JH1801 | 1 | 16 | 512 |
| JH1802 | 4 | 16 | 256 |
MIC50 and MIC90 of imipenem are 16 and 32 µg/mL and for faropenem are 512 and 512 µg/mL, respectively.