Table 2.

Frequency of spontaneous resistant mutants of M. abscessus ATCC 19977 recovered against T405 and imipenem at their individual MICs and when the T405 MIC is combined with avibactam at its individual MIC.

	Imipenem	T405	T405 + avibactam
Resistance frequency	1.9 × 10−7	2.0 × 10−6	5.8 × 10−9