Table 2.
Time (min) | Tissue/serum ratio of PZ-DHA (Mean ± SD) | ||||
---|---|---|---|---|---|
Liver/serum | Lungs/serum | Kidneys/serum | Spleen/serum | Brain/serum | |
15 | 0.14 ± 0.06 | 3.33 ± 1.51 | 0.66 ± 0.03 | 3.29 ± 1.56 | 0.51 ± 0.17 |
30 | 0.16 ± 0.08 | 2.04 ± 1.09 | 1.29 ± 0.22 | 3.17 ± 0.72 | 0.64 ± 0.11 |
60 | 4.68 ± 2.02* | 1.05 ± 0.014 | 0.81 ± 0.34 | 4.18 ± 1.01 | 0.95 ± 0.68 |
90 | 2.69 ± 2.17* | 3.51 ± 2.44 | 0.89 ± 0.26 | 5.24 ± 1.75 | 1.01 ± 0.19 |
120 | 1.03 ± 0.73 | 3.82 ± 1.74 | 2.71 ± 1.41* | 10.86 ± 8.42 | 1.31 ± 0.67 |
240 | 0.99 ± 0.23 | 4.97 ± 1.37 | 2.71 ± 1.08* | 16.15 ± 5.98* | 1.94 ± 0.75* |
Tissue/serum concentration ratios for PZ-DHA were compared at each time point, considering 15 min as the baseline (n = 4). *p < 0.05. (Liver/serum p = 0.0004; Kidneys/serum p = 0.002; Spleen/serum p = 0.003; Brain/serum p = 0.01).